PDF | Apoptosis is characterized by a series of dramatic Taylor RC, Cullen SP, Martin SJApoptosis: controlled demolition at the cellular level. Taylor, R.C., Cullen, S.P. and Martin, S.J. () Apoptosis Controlled Demolition at the Cellular Level. Nature Reviews Molecular Cell Biology, 9, Abstract I Apoptosis is characterized by a series of dramatic perturbations to the cellular architecture that contribute not only to cell death, but also prepare cells.
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Download PDF Cite this paper. Apoptosis is characterized by a series of dramatic perturbations to the cellular architecture that contribute not only to cell death, but also prepare cells for removal by phagocytes and prevent unwanted immune responses. Much of what happens during the demolition phase of apoptosis is orchestrated by members of the caspase family of cysteine proteases. These proteases target several hundred proteins for restricted proteolysis in a controlled manner that minimizes damage and disruption to neighbouring cells and avoids the release of immunostimulatory molecules.
Hideki Sakahira 17 Estimated H-index: Processing of engulfed apoptotic bodies yields T cell epitopes. Matteo Thd 20 Estimated H-index: Cited Source Add To Collection.
Apoptosis: controlled demolition at the cellular level.
S E Hall 1 Estimated H-index: Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs. Albert 51 Estimated H-index: Features of systemic lupus erythematosus in Dnase1-deficient mice. Markus Napirei 15 Estimated H-index: Immunosuppressive effects of apoptotic cells.
Voll 45 Estimated H-index: The Significance of Apoptosis. Wyllie 42 Estimated H-index: Cotter 60 Estimated H-index: Corpse clearance defines the meaning of cell death. John Savill 35 Estimated H-index: Masato Enari 16 Estimated H-index: The modulatory effects of commensal neisseriae on upper respiratory tract infections. Pre-clinical evaluation of amphiphilic silicone oligomers for scar remediation.
Emily Lynam 5 Estimated H-index: Ref Source Add To Ocntrolled.
Apoptosis: controlled demolition at the cellular level
Uriel Trahtemberg 9 Estimated H-index: Role in Myocyte Apoptosis and Myocardial Remodeling. Scofield 2 Estimated H-index: Louise von Stechow 6 Estimated H-index: Begg Netherlands Cancer Institute.
Olivier Sordet 2 Estimated H-index: Other Papers By First Author. TaylorKristen M. Establishing a blueprint for CEDdependent killing through identification of multiple substrates for this protease.
TaylorGabriela Brumatti. Critical Control Points cell [IF: Korsmeyer Howard Hughes Medical Institute.
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The biochemistry of apoptosis nature [IF: Hengartner Cold Spring Harbor Laboratory. Mitochondrial membrane permeabilization in cell death. Guido KroemerLorenzo Galluzzi. Are you looking for